Achieving the dream of whole-body rejuvenation for people now alive
The Human Rejuvenation Project aims to accelerate the progress of research into human, full-body rejuvenation. As a people, we can eliminate age-related illness and suffering and provide individual youthful health indefinitely for the people of the world.
From the foundation of a new understanding of aging, in the 21st century there has been an explosion of cutting-edge research performed by institutes and companies working on human rejuvenation treatments for the medical repair of the seven or so categories of age-related biological damage. Real progress has been made, and in fact, a number of these rejuvenation technologies are set to go to human clinical trials in the next several years.
The only way we, as a people, can achieve human rejuvenation in our lifetimes is to accelerate the progress of human rejuvenation research beyond its already impressive pace. To do that, we must replace certain paradigms of how we, as a society, treat aging. And we must replace these paradigms quickly.
The three primary paradigm shifts that we must make are:
- Rejuvenation research performed under the framework of an overall project
- Restructuring of the incentive ecosystem of rejuvenation research to promote sharing and cooperation
- Societal recognition of aging as a disease
Performed Under the Framework
Of an Overall Project
The latest consensus among rejuvenation researchers is that aging is a lethal synergy of several types of structural and physiological damage, all of which are the by-products of normal biological metabolism. Any one of the several types of aging damage can on its own lead to an eventual cascade of lethal, age-related illnesses.
That means that if progress in addressing any one of the types of damage falls behind, this will impede our overall progress toward our ultimate goal of robust, whole-body rejuvenation. In essence, our overall progress tracks the least-advanced of our research focus areas.
However, because of the profit incentives that drive much biomedical research, the areas of damage that receive the most research focus are too often those that have the greatest potential for profitable spin-offs, and not those areas that are the most neglected.
What we need is an overarching strategy for coordinating the attack on all types of damage, and we need a project to implement that strategy.
One of the purposes of The Human Rejuvenation Project is to manage and balance the effort across all types of damage:
- Track the research progress in addressing each type of damage
- Identify critical paths in the overall strategy
- Drive research resources to correct any imbalance in distribution of the effort
Restructuring of the
Incentive Ecosystem of
The Human Rejuvenation Project must provide incentives for research to be conducted in the framework of the project’s overarching strategy. But thus far, the way our society has been managing incentives for medical research is often at odds with any such overarching, global strategy.
Incentives for researchers in academia include:
- Career recognition
- Achieving tenure
- Occasionally, lucrative business opportunities
Incentives for private corporations (e.g. drug companies) include:
- Ownership of Intellectual Property (IP)
- Profit on the sale of drugs
Incentives for government agencies include:
- Cooperation with and promotion of private industry
- Satisfying the public
The way we have managed the ecosystem of these incentives has fostered:
- Competition over sharing
- The discouraging of results that might be negative for one research goal but yet useful overall
- Siloing rather than sharing of knowledge
- Unbalanced emphasis, favoring profitable research areas over neglected ones
One of the purposes of The Human Rejuvenation Project is to rethink and realign the incentive ecosystems of rejuvenation research to promote more collaboration and sharing to optimize progress toward our overarching goal.
Of Aging as a Disease
A mission with the level of challenge of bringing about human, full-body rejuvenation can be profoundly expedited by the wholehearted support of society, but can also be significantly impeded by the lack of such support.
Currently, our global society has in general not embraced the possibility of human rejuvenation, and that reluctance is manifest in that:
- National governments do not recognize aging itself as a disease
- The general public is reluctant to entertain the possibility of human medical rejuvenation